Kondrashova Natalia Aleksandrovna

The rectal way can be used to produce both local and systemic effect. When rectally administered medications are entered through nijneangarsk of the mucous membrane of the rectum, where the rectal venous (internal hemorrhoidal) plexus. The bioavailability with this route of administration is quite high, due to the abundant blood supply of the rectum, structure of the veins of this region, the so-called glomeruli or cavernous bodies, position them around the diameter, the presence of anastomoses between the cavernous bodies, the outflow of venous blood bypassing the liver that increases the rat...