List of publications on a keyword: «depression»

In the cases of majority of neurological diseases the symptoms of depression have significant influence on the worsening of the quality of patient’s life, regardless of the severity of the neurological disorders. In the most of neurodegenerative diseases the symptoms of depression often precede the appearance of neurological symptoms. Within recent years, numerous studies have been published demonstrating that disorders of depressive spectrum can be considered as a predictor of some types of dementia. Existing data regarding the methods of therapeutic intervention for depression in the clinical practice are rather scarce, scattered and often based on the «personal experience» of neurologists and psychiatrists. In some patients the diagnostics of depression in the context of neurological disorders can be difficult due to the difficulties in the establishing the contact with the patient as well as cognitive deviations related to neurological disorders. In order to facilitate this task, the effective screening diagnostic methods have been developed for the diagnosis of depression in the context of neurological diseases. The results of clinical studies performed within recent years confirm the important role of the neurologist for the evaluation and the treatment of the symptoms of depression, both at the initial stage and at the stage of remission. The purpose of the current review is to systematize the accumulated data on the disorders of depressive spectrum in the context of neurological practice, as well as to demonstrate the role of neurologist in the process of diagnosis and treatment of the symptoms of depression in neurological diseases.

In recent decades, sleep deprivation has evolved from a single experimental data set to the status of an effective and affordable therapeutic intervention used in daily clinical practice. The mechanism of action of this method is aimed at the same neurotransmitter systems and brain regions as antidepressants. As in the case of pharmacotherapy for sleep deprivation, it should be used under close supervision of a physician. Clinical effects with sleep deprivation are achieved much faster than with psychopharmacotherapy, but they are not long-term in nature. It is possible to improve the results using a combination of pharmacotherapy and sleep deprivation. The use of sleep deprivation in clinical conditions is aimed primarily at preventing depression and its recurrence, as well as in cases resistant to pharmacotherapy. In modern conditions, the method of sleep deprivation is a significant alternative to traditional approaches to therapy of depression.

Presently, a lot of data indicate that the disturbance of mechanisms underlying the regulation of sleep-waking cycle coincides with the mechanisms underlying the development of depression. The disturbance of circadian rhythms is one of the core factors in the genesis of the most affective disorders including depression, which indicates the role of the internal biological clock in the pathophysiology of affective disorders. The episodes of depression, mania or hypomania may result from the disturbances in endogenous biological timing. In this review, we have summarized the literature data obtained in animal models or in the patients with affective pathology, in which the connection between the function of sleep and depression was demonstrated. Specifically, we highlight the mechanisms underlying sleep dysfunction during depression (imbalance of circadian rhythms, melatonin metabolism and mechanisms of neuroinflammatory dysregulation) and provide an evidence for the link between sleep function and depression (sleep disturbances during depressive episodes, the effects of pharmacotherapy, chronotherapy, the effect of sleep deprivation, comorbidity of obstructive sleep apnea and depression).

Devoted to the current problem, depression during the session and the ability to eliminate it with the help of special techniques. The cause of depression is determined. The recommendations for improving the efficiency of the student.

Depression in an article is concerning in cancer patients, It makes the clinical picture of the cancer patients more complex, more difficult to be treated and it increases the risk of death, However, In conclusion, the rate of depression in cancer patients was 70%, There was an association between moderate depression and gender, between mild depression and cancer stage, between severe depression and difficulty in paying hospital fee, In addition, patients have a lot of desires in order to improve the quality of treatment at the hospital.

The purpose of the study is to evaluate anxiety and depression levels in cardiac patients after myocardial infarction. To achieve this goal the Beck's Depression Inventory and Beck's Anxiety Inventory were used in this study. The results showed that the levels of anxiety and depression were higher in women with myocardial infarction compared with men who had a myocardial infarction.