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The article considers the problem of genital prolapse in women. This is not a rare pathology to date. On the basis of clinical hospital, the authors conducted the study, the statistical data and the results of observations of patients. The researcher also described the classification and different ways of treatment of this pathology, developed a new method of surgical treatment of genital prolapse (circular hemostatic suture in vaginal extirpation of the uterus). At the end of the article the conclusions have been made.

According to the authors, appeared not long ago new psychoactive substances (designer drugs), including synthetic cannabinoids, derivatives of cathinone, phenethylamines, new stimulants, synthetic opioids, tryptamine derivatives, phencyclidine, piperazine, agonists of GABA (A/B) receptors have become a serious problem for both consumers and doctors. Consumers of these substances are attracted primarily by the intensity of psychoactive effects, as well as «legal purity», which is declared by shadow producers. This indicates that there are some significant difficulties of laboratory typing of new surfactants. Designer drugs when ingested, can affect a range of neurotransmitter pathways/receptors: dopamine, cannabinoid (CB1), GABA(A/B), 5-HT2A, glutamate, and k-opioid receptors (KOR), the imbalance of which leads to the development of polymorphic psychotic disorders.

According to the authors, the application of AkvaD3etrim on the background of symptomatic therapy of rickets and the vitamin D deficiency in children showed that, the drug leads to more dynamic performance improvement of calcium and phosphorus in blood, reduces the period of clinical symptoms and reduces the frequency of relapse of the disease.

The authors of this article describe the role of the development of pharmaceutical companies, producing competitive products. The researchers focus on the need for rational and coordinated actions of the Ministry of Health, Ministry of Industry and Trade, FAS and pharmaceutical producers.

The results allow to include colposcopy-uterine cytology (by histological indications), bacteriological and direct microscopic studies (if indicated by PCR – polymerase chain reaction) in the observation of pregnant women with abnormal cervical pathology. The ultrasound reveals not only pregnancy but also the prevalence of associated cervical and endometrial pathology, ovarian and helps to estimate the condition of the endometium, myometrium, bacteriological examination, diagnostics and to make correction on time with subsequent follow-up observation of the patients prior to delivery.

The article contains the results of holter ECG monitoring of 78 women with arterial hypertension of the II stage in the late fertile period with diagnosed left ventricular hypertrophy with hypoestrogenemy with "metabolically healthy" visceral obesity (MHVO) at the outpatient stage and the frequency of episodes of SMI in this category of patients. Patients with hypertension with concentric LVH have a greater potential for the development of relative coronary insufficiency, than women with its eccentric option. Limitation of coronary perfusion and reduced relaxation properties of hypertrophied myocardium in women with hypertension in late fertile period with diagnosed LVH may be a pathophysiological basis of the mechanism of myocardial ischemia, which is manifested in the form of episodes of SMI, which is significantly more often (p < 0,05) occurs in patients with metabolic "morbid"obesity.